Researcher China

Dr. Bin Li

Huazhong University of Science and Technology

Principal investigator on the world's first LHON gene therapy trial (NCT01267422, 2011) and subsequent rAAV2-ND4 trials at Huazhong University. Over 280 patients enrolled across multiple trials spanning 15 years of LHON gene therapy research.

Research focus

gene therapyrAAV2-ND4mitochondrial disease

Public profiles

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Recent publications

  • Long-term follow-up of a mitochondrial targeted AAV2-ND4 gene therapy

    2024

Relevant project findings

Dr. Bin Li’s research group at Huazhong University pioneered AAV2-based gene therapy for LHON ND4 mutations. Their three registered ClinicalTrials.gov trials (NCT01267422, NCT03153293, NCT03428178) represent the largest body of clinical evidence for this approach in the Asia-Pacific region.

Project outreach status

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